| Product | Licensee(s) | Indications | Preclinical | Phase I | Phase II | Phase III | Market |
|---|---|---|---|---|---|---|---|
| Crysvita® (Status in US only) | Kyowa Kirin Co., Ltd. & Ultragenyx Pharmaceutical Inc. | X-Linked Hypophosphatemia (XLH) Tumor-Induced Osteomalacia (TIO) | Complete | Complete | Complete | Complete | Work in Progress |
| Acamprosate | Confluence Pharmaceuticals | Fragile X Syndrome | Complete | Complete | Work in Progress | Not started | Not started |
| ABI-H0731 | Assembly Biosciences | Antiviral | Complete | Complete | Work in Progress | Not started | Not started |
| APX3330 | Apexian Pharmaceuticals & Ocuphire Pharma | Diabetic Retinopathy/Diabetic Macular Edema | Complete | Complete | Complete | Not started | Not started |
| Acamprosate | Confluence Pharmaceuticals | Autism Spectrum Disorder | Complete | Work in Progress | Not started | Not started | Not started |
| APX3330 | Apexian Pharmaceuticals | Cancer | Complete | Complete | Not started | Not started | Not started |
| APX3330 | Apexian Pharmaceuticals | IBD | Complete | Not started | Not started | Not started | Not started |
| CTI-1601 | Larimar Therapeutics, Inc. | Mitochondrial Disease | Complete | Complete | Work in Progress | Not started | Not started |
| MBX2019 | MBX Biosciences | Hypoparathyroidism (HP) | Complete | Complete | Not started | Not started | Not started |
| MBX 1416 | MBX Biosciences | Post-Bariatric Hypoglycemia (PBH) | Work in Progress | Not started | Not started | Not started | Not started |
| Precision Endocrine Peptide (PEPs) Therapeutics | MBX Biosciences | Rare Endocrine Disease(s) | Work in Progress | Not started | Not started | Not started | Not started |
| APX2009 | Apexian Pharmaceuticals, Inc. | Cancer, IBD | Work in Progress | Not started | Not started | Not started | Not started |
| APX2014 | Apexian Pharmaceuticals, Inc. | Cancer, IBD | Work in Progress | Not started | Not started | Not started | Not started |
| TRH nanoparticles | MVK Pharmaceuticals (Negotiating) | Anti-suicide/PTSD | Work in Progress | Not started | Not started | Not started | Not started |
| 16α-hydroxyprogesterone, deoxycorticosterone, 11-deoxycortisol biomarker assay (DocNatal) | Garbha Health, Inc. (dba Nixxi) | Pre-term labor | Work in Progress | Not started | Not started | Not started | Not started |
| PRMT5 Inhibitors | EQon Pharmaceuticals, LLC | Cancer and Inflammation | Work in Progress | Not started | Not started | Not started | Not started |
| Human Papilloma Virus (HPV) Antiviral Agents | Kovina Therapeutics, Inc. | Cervical, Anogenital, Oropharyngeal Cancers | Work in Progress | Not started | Not started | Not started | Not started |
| VSC 100 | Vascugen | Severe ischemic disease | Work in Progress | Not started | Not started | Not started | Not started |
| EMAP II Mab | Allinaire | Pulmonary Arterial Hypertension | Work in Progress | Not started | Not started | Not started | Not started |
| NICOTINAMIDE PHOSPHORIBOSYL- TRANSFERASE (NAMPT) INHIBITORS | Drax Therapeutics, Inc.* (Negotiating) | Pulmonary Arterial Hypertension | Complete | Not started | Not started | Not started | Not started |
| Molecular Diagnostics and Drug Development for Mental Health | MindX Sciences Inc. | Suicide, Pain, Stress, Aging | Work in Progress | Not started | Not started | Not started | Not started |
| Soluble Epoxy Hydrolase Inhibitors (SH-11037) | Exclusive Option | Ocular Disease | Work in Progress | Not started | Not started | Not started | Not started |
| Ferrochelatase Inhibitors (Griseofulvin) | Exclusive Option | Ocular Disease | Work in Progress | Not started | Not started | Not started | Not started |
| Optate | N/A | COVID-19 | Complete | Work in Progress | Not started | Not started | Not started |
| STAT3 Inhibitors | N/A | Cancer | Work in Progress | Not started | Not started | Not started | Not started |
| Survivin Inhibitors | N/A | Cancer | Work in Progress | Not started | Not started | Not started | Not started |
| GroEL/ES Inhibitors | N/A | Anitmicrobial treatments | Work in Progress | Not started | Not started | Not started | Not started |
| SHP2 Inhibitors | N/A | Cancer, Autoimmune Disease | Work in Progress | Not started | Not started | Not started | Not started |
| Voltage-gated calcium channel (CaVβ) Inhibitors | N/A | Neuropathic pain | Work in Progress | Not started | Not started | Not started | Not started |
| Novel antibiotics | N/A | Vibrio infections | Work in Progress | Not started | Not started | Not started | Not started |
| Endocytosis Inhibitors (RAP) | N/A | Kidney Disease (AKI) | Work in Progress | Not started | Not started | Not started | Not started |
| Insulin Analogs (including GRIs) | N/A | Diabetes | Work in Progress | Not started | Not started | Not started | Not started |
| Ral GTPase Inhibitors | N/A | Cancer | Work in Progress | Not started | Not started | Not started | Not started |
| cGMP Related Phosphodiesterases inhibitors | N/A | Polcystic kidney disease | Work in Progress | Not started | Not started | Not started | Not started |
| HOTAIR/PRC2 interaction inhibitors (peptide-nucleic acid based) | N/A | Ovarian cancer | Work in Progress | Not started | Not started | Not started | Not started |
| Poly(ADP-ribose) polymerase inhibitors (PARPi) | N/A | Cancer | Work in Progress | Not started | Not started | Not started | Not started |
| Rotavirus Expression Platform | N/A | Rotavirus/Norovirus Infections | Work in Progress | Not started | Not started | Not started | Not started |
| TRVP4 antagonists | N/A | Hydrocephalus | Work in Progress | Not started | Not started | Not started | Not started |
| Treatments for hydrocephalus | N/A | Hydrocephalus | Work in Progress | Not started | Not started | Not started | Not started |
| miRNA Therapies | N/A | Pancreatitis | Work in Progress | Not started | Not started | Not started | Not started |
| miRNA Therapies | N/A | Pancreatitis | Work in Progress | Not started | Not started | Not started | Not started |
| ASC-Secretome | N/A | Neurodegenerative Diseases including ALS | Work in Progress | Not started | Not started | Not started | Not started |
| Novel siRNS Therapies | N/A | Alzheimers | Work in Progress | Not started | Not started | Not started | Not started |
| Cell Based Therapies | N/A | Bone Metastatsis | Work in Progress | Not started | Not started | Not started | Not started |
| Tamm-Horsfall Protein/Uromodulin | N/A | Kidney Disease | Work in Progress | Not started | Not started | Not started | Not started |
| Antisense Oligos targeting miRNAs | N/A | Neurodegeneration disease/Alzheimers | Work in Progress | Not started | Not started | Not started | Not started |
| Activin A and B Inhibitors | N/A | Liver Fibrosis | Work in Progress | Not started | Not started | Not started | Not started |
| Inhibitors for muscle tissue remodeling | N/A | Pulmonary Arterial Hypertension | Work in Progress | Not started | Not started | Not started | Not started |
| Novel biomarker and target for treating pulmonary hypertension | N/A | Pulmonary hypertension | Work in Progress | Not started | Not started | Not started | Not started |
